Mesoscale blood cell sedimentation for processing millilitre sample volumes.

نویسندگان

  • C Galligan
  • J Nichols
  • E Kvam
  • P Spooner
  • R Gettings
  • L Zhu
  • C M Puleo
چکیده

We demonstrate the efficient separation of blood cells from millilitre volumes of whole blood in minutes using a simple gravity sedimentation device. Blood cell and plasma separation is often the initial step in clinical diagnostics, and reliable separation techniques have remained a major obstacle for the success of point-of-care or remote diagnostics. Unlike plasma collection devices that rely solely on microchannels that restrict sample volume and throughput, we demonstrate the use of a hybrid micro/mesoscale sedimentation chamber to enable >99% capture of cells from millilitre blood samples in less than two minutes.

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عنوان ژورنال:
  • Lab on a chip

دوره 15 16  شماره 

صفحات  -

تاریخ انتشار 2015